FP5-2001-39266 BEST – Biomolecular rEcognition by integrated Smart-sensor Technology
The goal of the research in which this assessment project is framed, is the design, realization on standard CMOS technology and testing of a field-effect based integrated electronic device suitable for the detection of bio molecular recognition processes on a sensing surface where analysis takes place. The application domain is the medical self-test for many diseases related to DNA (e.g. tracking the activity of thousands of genes at once with a matrix of such devices would enable to monitor how patterns of gene expression change in diseases such as cancer) and proteins (e.g. monitoring the expression of nuclear proteins with specific alterations could bring to prompt diagnostic assessments). Result of the assessment phase is to establish if the proposed field effect devices realized on low-cost technology are feasible for the detection of such interactions. The goal of the research in which this assessment project is framed, is the design, realization on standard CMOS technology and testing of a field-effect based integrated electronic device suitable for the detection of bio molecular recognition processes on a sensing surface where analysis takes place. The application domain is the medical self-test for many diseases related to DNA (e.g. tracking the activity of thousands of genes at once with a matrix of such devices would enable to monitor how patterns of gene expression change in diseases such as cancer) and proteins (e.g. monitoring the expression of nuclear proteins with specific alterations could bring to prompt diagnostic assessments). Result of the assessment phase is to establish if the proposed field effect devices realized on low-cost technology are feasible for the detection of such interactions.
https://cordis.europa.eu/project/id/IST-2001-39266
